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Point of Care Technologies - Diagnostics

This program supports the technology development of rapid in-vitro diagnostic technologies and monitoring platforms that provide real time medical evaluation and analysis of the disease status or condition at the time and place of patient care.

Emphasis

The program includes the delivery of healthcare that is safe, effective, timely, patient-centered, efficient, and available in centralized and decentralized locations. The emphasis is on developing technologies driven by clinical needs. Examples of technology development areas in this program include but are not limited to disposable lateral flow assays, nucleic acid testing platforms, glucose monitoring devices, etc.

Program priorities

  • Rapid: ideal diagnostic test time to identify species and determine drug susceptibility profiles, process the clinical sample (if appropriate), and detection and delivery of the final test result during a single interaction
  • Sensitive: sensitivity should be equivalent to or exceed current standards for proposed targets from the same sample type
  • Specific: specificity should be equivalent to or exceed current standards for proposed targets from the same sample type
  • Easy-to-use: integrated, closed sample-to-answer system with automated data analyses and/or result presentation and with minimal operator training and expertise required
  • Cost-effective: projected production and operating costs should be consistent or an improvement on commonly used platforms

Featured programs and resources

Point of Care Technology Research Network

NIBIB created the Point-of-Care Technologies Research Network (POCTRN) to drive the development of appropriate point-of-care diagnostic technologies through collaborative efforts that merge scientific and technological capabilities with clinical need. Today, with the support of the National Heart, Lung and Blood Institution, National Institute of Allergy and Infectious Diseases, National Center for Complementary and Integrative Health, Fogarty International Center, Office of Behavioral and Social Sciences Research, Office of AIDS Research and Office of Disease Prevention, the following Centers comprise POCTRN.

  • Point of Care Technology Research Network Center- Coordinating Center
  • Center for Point-of-Care Technologies Research for Sexually Transmitted Diseases
  • The Center for Innovation in Point of Care Technologies for HIV/AIDS at Northwestern (C-THAN)
  • Atlanta Center for Microsystems Engineered Point-of-Care Technologies (ACME-POCT)
  • The Center for Advancing Point of Care in Heart, Lung, Blood and Sleep Diseases

Visit www.poctrn.org for detailed information.

Point of Care Technology listserv

The e-newsletter serves as an information outlet to the Point of Care Technology community on current activities and initiatives involving point of care technology research supported by the National Institutes of Health. Join the NIBIB Point of Care Technologies listserv.

Notice of Special Interest in Physiological Monitoring and Point of Care Technologies for Trauma Care

 
Grant Number Project Title Principal Investigator Institution
1-R41-EB029284-01 Lightweight optoimpedance sensors enabling early detection of the physiological response to injury and illness Ryan Halter Multivariate Systems, Inc.
5-R01-EB023607-05 A Reaction- Diffusion-Based Approach for Nucleic Acid Quantification Changchun Liu University of Connecticut Sch of Med/Dnt
5-R44-EB023408-04 Lateral flow immunoassay for rapid diagnosis of tinea capitis and onychomycosis Amanda Burnham-Marusich Dxdiscovery, Inc.
5-R21-EB027865-02 Leveraging Artificial-Intelligence to Profile and Enhance Phenotypic Plasticity for Second Injury Prevention: An Innovative Precision Medicine Platform to Revolutionize Injury Care Adam Kiefer Univ of North Carolina Chapel Hill
1-R21-EB030349-01 Paper-Analytical Device for Saliva Biomarker Diagnostics Charles Henry Colorado State University
1-R21-EB030305-01 BehaviorSight: Privacy enhancing wearable system to detect health risk behaviors in real-time. Nabil Alshurafa Northwestern University at Chicago
1-R43-EB030874-01 hANDY-i(TM): A non-invasive, dual-sensor handheld imager for intraoperative preservation of parathyroid glands Jaepyeong Cha Optosurgical, Llc
1-R43-EB030890-01 An Interoperable HL7 FHIR-based Medical Device Data System (MDDS) For Accessing And Integrating Live Point-Of-Care Data From High-Acuity Bedside Patient Monitoring Equipment John Osborne Medicollector, Llc
5-R44-EB024288-05 Point-of-care device to identify patients at risk for preeclampsia Shrikumar Nair Affinergy, Llc
5-R21-EB025499-02 Detection of early-stage, active tuberculosis infection and disease progression during treatment using a rapid, inexpensive and simple-to-use microneedle patch diagnostic platform Mark Prausnitz Georgia Institute of Technology