2015 Design by Biomedical Undergraduate Teams (DEBUT) Challenge Winners

First Place

Viral Diagnostic Technology, Lehigh University

Kathryn Kundrod, Jay Fraser, Kaylynn Genemaras, Paul Schroder, Andrew D'Onofrio

The Viral Diagnostic Technology device addresses the need for a more accessible point-of-care viral load diagnostic device for HIV treatment monitoring. A majority of people living with HIV reside in resource-limited settings where traditional laboratory-based tests are not accessible. Current point-of-care technologies in the market or under development remain expensive and complex. The undergraduate team of five students from Lehigh University in Bethlehem, Pennsylvania, has developed a system that meets the World Health Organization’s minimum detection requirements while also delivering results in under an hour. In addition, it involves lower instrumentation and pre-test costs and is less complex than other currently available technologies available. This device can help determine if a patient’s medications are having the desired effect of decreasing the amount of virus in the bloodstream. The design has the potential to increase accessibility to viral load testing globally.

Viral Diagnostic Technology.pdf

Second Place

FreePulse, University of Texas at Austin

Courtney Koepke, Reece Stevens, Abhishek Pratapa, James Yao, Ajay Rastogi, Avery Coker, Anamika Chourasia, Peter Yu, Zeba Bernat, Alina Schroeder, Faiz Baqai, Akash Patel

FreePulse is a device that aims to provide a durable, reliable, and accessible patient monitor. Patient monitors are mechanical and electrical medical devices designed to continually monitor a patient’s vital signs in order to identify respiratory or cardiac distress. The high cost of current patient monitors forces hospitals in low-income and developing areas to largely depend on outside donations for new devices, an infrequent and unreliable source of critical equipment. The team from the University of Texas at Austin developed FreePulse, a low-cost device to provide basic monitoring for heart rate, electrocardiogram signals (ECG), and percent saturated oxygen (SpO2). Visual alerts are implemented to warn nurses if a patient begins to experience cardiac or respiratory distress, matching the capability of current market devices. A replaceable backup battery and uninterrupted power circuit ensures that the device continues to function even in unstable power conditions. While these features were included in the design so it would be functional in developing countries, they are also relevant in many low-income and rural areas as well.

FreePulse.pdf

Third Place

RESONAIR: Unblocking Cystic Fibrosis, Stanford University

Kevin Bui, Justo Caballero, Elvis Ikwa, Allison Mateo, Shivani Torres

RESONAIR is a portable, wearable, vibrating device—discretely contained within a backpack—that is able to quickly dislodge mucus from the airway, caused by cystic fibrosis (CF). CF is a severe, genetic disorder that that leads to an overproduction of thick mucus in a patient’s airways, resulting in respiratory problems, lung infections, hospitalizations, and decreased life expectancy and affects 30,000 people in the U.S. and 70,000 people worldwide. CF is a chronic disease that requires constant treatment to effectively manage the symptoms. However, low treatment compliance is a huge issue among the CF population. This leads to respiratory problems and chronic lung infections, resulting in hospitalizations, decreased quality of life, and lower life expectancy. RESONAIR is easy to use and optimizes therapy by allowing the patient to control the force while staying in the lungs’ resonant frequency range. This customizability is a feature not readily available in current devices. RESONAIR was developed by a team of students from Stanford University and attempts to increase compliance, reduce time spent on active treatment, improve quality of life, and lower overall healthcare costs.

RESONAIR Unblocking Cystic Fibrosis.pdf

Honorable Mentions

A Novel Point-of-Care Diagnostic for SexuallyTransmitted Infections, Boston University

Gil Covarrubias, Danielle Conneely, Courtney Ellenson, Nelson Boland

The microfluidic device captures, amplifies, and detects gonorrhea DNA from patient samples such as urine.

POC Diagnostic for SexuallyTransmitted Infections.pdf

Low Cost Neonatal Incubator for Developing World Hospitals, Rice University

Zaid Haque, Bailey Flynn, Carissa Livingston, Caleb Owsley, Amanda Boone

A low-cost neonatal incubator for use in the developing world. Its double-walled design utilizes two commercial heating pads to warm an infant and includes safety alarms and a temperature feedback system.

Low Cost Neonatal Incubator for Developing World Hospitals.pdf

Luminox – Reflectance based pulse oximeter for low resource settings, Rice University

Pablo Henning, Chloe Nguyen, Samantha Olvera, Kamal Shah, Erica Skerrett

Luminox is a reusable, durable, reflectance pulse oximeter for use in pediatrics in developing countries.

Luminox - Reflectance based pulse oximeter for low resource settings.pdf

OstoCare: Ostomy Continence Device, Columbia University

Sandeep Palepu, Shruthi Nammalwar, Wilson Ho, Molleshree Karna, Alan Czemerinski

OstoCare is a device that is compatible with all ostomy bag systems on the market and works to minimize leakages and leakage related issues while remaining discreet, biocompatible, easy to use, and comfortable.

OstoCare- Ostomy Continence Device.pdf

Smart Walker Device, Michigan State University

Trevor Dirheimer, Jeffrey Hancock, Dominic Hill, Yakov Kochubievsky, Sean Moore

The Smart Walker device consists of two sensors with microcontroller integration and a rechargeable power supply and enables drop-off detection from a safe stopping distance.

Smart Walker Device.pdf

TocoTrack: Uterine Contraction Monitoring, Johns Hopkins University

Malvi Hemani, Huilei Wang, Kunal Patel, Wooyang Son, Jason Park, Melissa Lin, Nolan Benner, Yunchan Chen

TocoTrack, which is a novel uterine contraction monitor designed for developing countries. When strapped on, the device measures the frequency and duration of contractions and outputs the data in partograph form to an LCD display, which midwives can copy over to their paper partograph.

TocoTrack- Uterine Contraction Monitoring in the Developing World.pdf

Update, September 11, 2015: “This story has been updated to reflect a change in the winners”