This division supports the development and demonstration of modular platform technologies (without preference for any disease or application) that manipulate and interface with biology to enable new paradigms of clinical intervention for human health.
Division of Discovery Science & Technology (Bioengineering)
Science Highlights ·A change of instructions in a computer program directs the computer to execute a different command. Similarly, synthetic biologists are learning the rules for how to direct the activities of human cells.
Grantee News ·Understanding the physics of clot contraction could potentially lead to new ways to treat bleeding problems and clotting problems.
Grantee News ·Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treatment rescued disease symptoms in animal models, enabling long-lasting production of healthy blood cells, and could inspire a therapeutic strategy for SCD.
Grantee News ·Hydrogels are commonly used inside the body to help in tissue regeneration and drug delivery. However, once inside, they can be challenging to control for optimal use. A team of researchers is developing a new way to manipulate the gel -- by using light.
NIBIB in the News ·Thinking back to a year ago when terror struck worldwide and the full weight of the Covid-19 pandemic began to set in, NIH quickly mobilized on multiple fronts—one of which was the RADx initiative, with the goal of helping to meet the huge demand for fast, accurate Covid-19 tests. Source: NIH Record.