Therapeutic Medical Devices

This program supports the design and development of non-imaging devices intended for therapeutic interventions.


Emphasis is on engineering non-imaging devices, components, and control systems for in vivo therapeutic interventions directed toward overcoming a technological challenge that limits biomedical application. Relevant examples include but are not limited to:

  • rehabilitative or curative – wearable, orthotic, or implantable devices to restore health after disease or illness
  • assistive – wearable, orthotic, prosthetic, robotic, or implantable devices to replace or supplement capability lost due to chronic conditions
  • preventative – wearable, orthotic, or implantable devices to avoid the onset of acute or chronic conditions, including secondary complications


The development of detector modules and sensors is supported by the NIBIB Bioanalytical Sensors program, the development of point of care devices is supported by the NIBIB Point of Care Technologies program, and the development of tools for surgical interventions is supported by the NIBIB Surgical Tools program.

See funding opportunity announcements and other information about Developing Medical Devices to Treat Pain

Grant Number Project Title Principal Investigator Institution
1-DP2-EB022357-01 Spinal cord neural interface for neuroprosthetics in a primate model Abhishek Prasad University of Miami Coral Gables
5-R01-EB018956-04 Thermal Assisted Gene Electro Transfer to the Skin Richard Heller Old Dominion University
1-R15-EB026196-01 Characterization of Ventricular Catheter Performance for Improved Treatment of Pediatric Hydrocephalus Stephanie Termaath University of Tennessee Knoxville
5-R01-EB023943-03 Enabling Technology for Safe Robot-assisted Surgical Micromanipulation Iulian Iordachita Johns Hopkins University
5-R21-EB024635-02 Next Generation Neural Interfaces Based on Axonal Confinement in Micro-Channel Electrode Arrays Erkin Seker University of California at Davis
5-R21-EB024957-02 Intraoperative Measurement of Ligament Tension to Guide Knee Arthroplasty Darryl Thelen University of Wisconsin-Madison
5-R25-EB025791-02 Clinical Immersion Program to Enhance Interdisciplinary Biomedical Engineering Senior Capstone Design Ellen Brennan-Pierce Colorado State University
5-R01-EB024403-03 Targeted chemotherapy delivery and capture Rahmi Oklu Mayo Clinic Arizona
5-R25-EB023839-02 Interprofessional Design and Entrepreneurship in Medical Devices at UC San Diego Adam Engler University of California, San Diego
5-R25-EB025793-02 Multidisciplinary medical product design education as a foundation to drive quality improvement through innovation in patient care Mark Gartner University of Pittsburgh at Pittsburgh