Emphasis

Emphasis is on the design and wholesale construction of new biological parts and systems and the re-design of existing, natural biological systems for tailored purposes.

Additional emphasis

Examples of tools to enable synthetic biology approaches include but are not limited to:

• synthetic biological circuits for control and decision-making (Biomaterials and Biomolecular Constructs program, Engineered Cells program, Engineered Tissues program)
• design and evolution systems to construct biomolecules and biological systems (Biomaterials and Biomolecular Constructs, Engineered Cells program)
• advanced genome editing machinery for DNA manipulation (Biomaterials and Biomolecular Constructs program)

Examples of the use of synthetic biology approaches to develop technologies that are relevant to other NIBIB-supported program areas include but are not limited to:

• synthesis of biomaterials (Biomaterials and Biomolecular Constructs program)
• spatiotemporal control of tissue growth (Engineered Tissues program)
• selective detection of biomarkers (Biosensors and Physiological Detectors program)
• regulated, on-demand delivery of therapeutic agents (Engineered Cells program)
• molecular imaging of cellular function (Molecular Imaging program)

Notes

Inquiries and applications are managed by the Synthetic Biology for Technology Development program, and awarded grants are managed in their relevant NIBIB programs.