In April 2003, the Interagency Modeling and Analysis Group (IMAG) was formed; starting from a working group comprised of program staff from nine Institutes of the National Institutes of Health (NIH) and three directorates of the National Science Foundation (NSF). IMAG now represents over 100 program staff from multiple government agencies in the United States and Canada.
Since its creation, this group has convened monthly through virtual meetings and at various locations of the IMAG participants. All IMAG participants are involved in managing research programs in biomedical, biological and behavioral systems that require the development of new and novel modeling and analysis methods.
The purpose of the IMAG is to provide an open forum for communication among government representatives to share updates on individual programs from the various IMAG agencies, and to plan trans-agency activities that will have a broad impact on the communities served by the IMAG.
The Multiscale Modeling (MSM) Consortium
In 2003, the IMAG recognized that the modeling community was on the forefront of thinking across the biological continuum, rather than just focusing at one scale or level of resolution. In addition, the IMAG identified a strong desire among modelers to form multi-disciplinary partnerships across varied research communities. This led to the development in 2004 of the Interagency Opportunities in Multiscale Modeling in Biomedical, Biological, and Behavioral Systems Solicitation. The 24 awardees from this solicitation subsequently formed the MultiScale Modeling (MSM) Consortium in 2006. The MSM Consortium has now grown to include over 100 projects relevant to multiscale modeling.
Top Model Video Competition
The IMAG Public Dissemination and Education Task Force held a Top Model Video Competition to engage undergraduate students in the field and share examples of how computational modeling can impact human health. The winners received their awards the 2019 MSM Consortium meeting in March. View the video entries from the links provided here:
Modeling the obesity epidemic. Researchers from the Johns Hopkins University develop multiscale models to identify interventions to reduce the incidence of childhood obesity.
Multiscale Modeling of Infection Second Place
Modeling macrophage heterogeneity in Salmonella infection. Researchers at the Allen Discovery Center at Stanford University in Collaboration with the University of Virginia study salmonella infections and identify ways to combat antibiotic resistance using multiscale modeling.
Silk Integrated Theory Theory Experiment Project Third Place
Modeling the silk integrative theory experiment project. A research team from Tufts University and the Massachusetts Institute of technology (MIT) use multiscale modeling to design novel biomaterials for tissue engineering and drug delivery.
Multiscale Modeling in Sickle Cell Disease Fourth Place
A research team led by Dr. Karniadakis at Brown University uses multiscale modeling to study how sickle cell disease causes tissue and organ damage.
The MSM Consortium provides opportunities to:
- network with other MSM investigators, MSM participants, and projects;
- easily converse with program officers from ten government agencies and IMAG participants from the U.S. and Canada;
- participate in focused Working Group discussions on the wiki;
- participate in virtual scientific presentations by all Working Groups throughout the year;
- participate in annual meetings of the MSM Consortium and IMAG/MSM events;
- learn about the latest modeling and MSM-related activities from around the world; and
- access various resources for modeling
The MSM Consortium was involved in producing the IMAG Futures Report. Download PDF
All activities of the MSM Consortium are live on the IMAG wiki. Researchers interested in joining the MSM Consortium should visit: MSM Consortium FAQs.
All researchers are welcome to join individual MSM Consortium Working Groups by contacting the Working Group Leads listed at the link above.
No funding opportunities are available at this time. Please check back for future updates.
Models to predict protein biomaterial performance
Tufts University Medford
Multiscale Modeling of Wound Healing
North Carolina State University Raleigh
Microconnectomics of neocortex: a multiscale computer model
Suny Downstate Medical Center
Predictive Multiscale Modeling of Microbial Consortia Biofilms
Montana State University - Bozeman
Multiscale Modeling of Facet Capsule Mechanobiology
University of Minnesota