Explore more about: Cartilage Repair

Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide. To combat this issue, NIBIB-funded researchers are developing an implantable, biodegradable film that helps to regenerate the native cartilage at the site of damage. Their study, performed in rabbits, could be an initial, important step in the establishment of a new treatment.

Scientists have developed a method to bioprint a type of cartilage that could someday help restore knee function damaged by arthritis or injury.

Thin tissue grafts and flexible electronics have a host of applications for wound healing, regenerative medicine and biosensing. A new device inspired by an octopus's sucker rapidly transfers delicate tissue or electronic sheets to the patient, overcoming a key barrier to clinical application.

Artificial intelligence can speed the development of 3D-printed bioscaffolds that help injuries heal, according to researchers.

Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.

Bioengineers print 3D implants with layered cells destined to become distinct combinations of tissue, like bone and cartilage. The scaffolds degrade over time to leave the natural tissues in place.

The development of new bone can be a multistep process: first, stem cells differentiate into cartilage cells. Next, the cartilage cells become bone cells. But that's not all: the cells must experience some mechanical stresses during the transformation in order to transform efficiently from stem cells to bone cells.

Bioengineers used bone engineered in a 3D-printed mold and grown alongside the ribs of sheep to successfully replace a portion of the animals’ jaw bones.

NIBIB-funded researchers have designed a new class of 2D nanomaterials that are disc-shaped and flat on the surface, to aid in treatments for cartilage repair.

NIBIB-funded researchers have developed a 3D-printed scaffold coated in aggrecan, a native cartilage component, to improve the regeneration of cartilage tissue in joints.