Scientists report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems. The new method was developed, say the researchers, to deliver an immune system 'uncloaking' device directly to cancer cells.
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Macrophages are white blood cells that accumulate in tumors, where they aid cancer progression. Now scientists have identified a surface protein found only on the macrophages residing in tumors, exposing a target for precise tumor treatments.
NIBIB researchers have designed a nanoparticle that generates radiation-induced oxygen free radicals in the low-oxygen center of tumors, dramatically increasing tumor destruction.
An NIH-funded team at the University of Colorado (UC) has assembled a clearer picture of the molecular activity that occurs when nanoparticles injected into the body are marked for immune system attack.
Nanogenerator’s electrical pulses provide beneficial outcomes with no side effects – rat study.
Researchers have developed nanorobotic agents that can navigate through the bloodstream to administer a drug by targeting the active cancerous cells of tumors.
Researchers have developed a computer model that will aid in the design of nanocarriers.
Researchers develop a way to prepare mesenchymal stem cells leading to the production of more native stem cells, and label them with an iron-oxide nanoparticle.
Researchers describe a 'nanoblade' that can slice through a cell's membrane to insert mitochondria.
Researchers at MIT and Brigham and Women’s Hospital have developed nanoparticles that can deliver anti-obesity drugs directly to fat tissue.