Explore more about: Synthetic Biology

August 19, 2021
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A Rice University bioengineer and her Brown School of Engineering team were awarded an NIH grant to create gene activity sensors and activators that hold unmatched potential for the treatment of infectious diseases, diabetes, genetic disorders, and cancer. Source: AZO Life Sciences
June 25, 2021
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A change of instructions in a computer program directs the computer to execute a different command. Similarly, synthetic biologists are learning the rules for how to direct the activities of human cells.
July 23, 2021
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Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treatment rescued disease symptoms in animal models, enabling long-lasting production of healthy blood cells, and could inspire a therapeutic strategy for SCD.
July 26, 2021
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Chase Cornelison's research at UMass Amherst explores the proliferating power of cancer cells to treat spinal cord injuries and restore function following brain damage, promising research that has earned an NIH Trailblazer Award. Source: News Medical.
January 7, 2021
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Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy.
June 29, 2021
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Research into what is known as the gut-brain axis continues to reveal how the brain and gut influence each other’s health and well-being. Now researchers are endeavoring to learn more about gut-brain discourse using a model system built in a lab dish.
November 25, 2019
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Researchers have designed a more precise and versatile genome editing system, named prime editing, that harnesses the power of CRISPR-Cas9 in combination with another protein, reverse transcriptase, to directly edit DNA in human cells.
August 6, 2021
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Mothers and children in low resource communities often suffer from micronutrient deficiencies. Now NIBIB-funded researchers have developed a system that can be used for tests to rapidly identify blood micronutrient levels in remote areas with limited healthcare infrastructure.
October 8, 2019
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Biological engineers can program bacteriophages to kill different strains of E. coli by making mutations in the protein that the viruses use to bind to host cells. These engineered phages are less likely to provoke resistance in bacteria, and could help to overcome antibiotic resistance.
July 26, 2021
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Researchers funded by NIH have developed an imaging method that reveals a much more diverse and flexible DNA-protein chromatin chain than previously thought. The result suggests a nimbler structure to regulate gene expression, and provide a mechanism for chemical modifications of DNA to be maintained as cells divide.