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Bioelectric Engineering

This program supports the design, development, and demonstration of bioelectric technologies for biomedical intervention.

Emphasis

This division supports projects developing and demonstrating new approaches to control/program biology for biomedical intervention, without preference for any particular disease or application.

Emphasis in this program is on engineering new bioelectric materials, sensors, actuators, and other parts and modules to interface and communicate with human biology and engineered systems for biomedical intervention. These parts and modules act as biotransducers to convert electric energy to biological action. Projects should be directed toward overcoming a technological challenge that limits biomedical adoption. This program encourages projects that use a design-build-test approach. 

Examples of bioelectric parts and modules include but are not limited to: 

  • electrically conductive scaffolds for modulating tissue 
  • low-temperature plasma electrodes for biofilm mitigation 
  • electrodes for prosthetics
  • injectable electronic meshes for tissue interfaces

Additional Emphasis

Additional emphasis in this program is on the development of screening and processing tools and the discovery of design principles to design, build, and test engineered bioelectric modules. 
 

Notes

The development of integrated systems is supported by the Bionic and Robotic Systems program and Synthetic Biology and Biomimetic Systems program.

 
Grant Number Project Title Principal Investigator Institution
1-R15-EB024930-01A1 Dynamically Controlled Plasma Scalpel for Wound Debridement Jim Browning Boise State University
5-R21-EB024693-03 Low-temperature corona plasma discharge treatment of bacterial biofilms in the cardiovascular environment Sean Knecht Pennsylvania State University-Univ Park
5-R01-EB020006-04 3D Spheroid Model of Adipose Pathophysiology Amol Janorkar University of Mississippi Med Ctr
5-UG3-EB028094-02 A Human iPSC-based 3D Microphysiological System for Modeling Cardiac Dysfunction in Microgravity Deok-Ho Kim University of Washington
8-U01-EB029374-02 Human microtissues for in situ detection and functional measurement of adverse consequences caused by genome editing Todd Mcdevitt J. David Gladstone Institutes
8-U01-EB029371-02 Single Cell Profiling To Define Biomarkers Of Photoreceptor Dysfunction After Gene Editing Within PSC-Derived Organoids Krishanu Saha University of Wisconsin-Madison
5-U01-EB025138-03 Bioelectric monitoring and control of the heart Jeffrey Ardell University of California Los Angeles
5-R21-EB025945-02 An artery-on-a-chip system containing blood outgrowth endothelium as a model of vaso-occlusion and drug testing in sickle cell disease Abhishek Jain Texas Engineering Experiment Station
5-R21-EB026180-02 Multimodal Probing of Neural Activity Using Transparent Microelectrode Arrays Duygu Kuzum University of California, San Diego
5-R01-EB025596-02 A 3D human tissue-engineered lung model to study immune responses to Respiratory Syncytial Virus Susan Kovats Oklahoma Medical Research Foundation