Bioelectric Engineering

This program supports the design, development, and demonstration of bioelectric technologies for biomedical intervention.


This division supports projects developing and demonstrating new approaches to control/program biology for biomedical intervention, without preference for any particular disease or application.

Emphasis in this program is on engineering new bioelectric materials, sensors, actuators, and other parts and modules to interface and communicate with human biology and engineered systems for biomedical intervention. These parts and modules act as biotransducers to convert electric energy to biological action. Projects should be directed toward overcoming a technological challenge that limits biomedical adoption. This program encourages projects that use a design-build-test approach. 

Examples of bioelectric parts and modules include but are not limited to: 

  • electrically conductive scaffolds for modulating tissue 
  • low-temperature plasma electrodes for biofilm mitigation 
  • electrodes for prosthetics
  • injectable electronic meshes for tissue interfaces

Additional Emphasis

Additional emphasis in this program is on the development of screening and processing tools and the discovery of design principles to design, build, and test engineered bioelectric modules. 


The development of integrated systems is supported by the Bionic and Robotic Systems program and Synthetic Biology and Biomimetic Systems program.

Grant Number Project Title Principal Investigator Institution
1-R15-EB024930-01A1 Dynamically Controlled Plasma Scalpel for Wound Debridement Jim Browning Boise State University
5-R01-EB021908-04 GuMI: New In Vitro Platforms to Parse the Human Gut Epithelial-Microbiome-Immune Axis Rebecca Carrier Northeastern University
5-R01-EB024860-03 Combined No Onset Waveform for KiloHertz Frequency Alternating Current Nerve Block Niloy Bhadra Case Western Reserve University
5-R01-EB000244-40 A new high-throughput gastrointestinal tract explant platform for drug formulation discovery and metabolic disease modulation Robert Langer Massachusetts Institute of Technology
5-R21-EB024693-03 Low-temperature corona plasma discharge treatment of bacterial biofilms in the cardiovascular environment Sean Knecht Pennsylvania State University-Univ Park
5-R21-EB025270-02 Multiscale Stereolithogrphic Bioprinting of Stage-Matching Vascularized Tumor Models Yu Zhang Brigham And Women'S Hospital
5-R21-EB025406-02 Engineered Glioblastoma Tumor Immunity for Personalized Immunotherapy Weiqiang Chen New York University
5-UG3-EB028094-02 A Human iPSC-based 3D Microphysiological System for Modeling Cardiac Dysfunction in Microgravity Deok-Ho Kim University of Washington
8-U01-EB029374-02 Human microtissues for in situ detection and functional measurement of adverse consequences caused by genome editing Todd Mcdevitt J. David Gladstone Institutes
8-U01-EB029371-02 Single Cell Profiling To Define Biomarkers Of Photoreceptor Dysfunction After Gene Editing Within PSC-Derived Organoids Krishanu Saha University of Wisconsin-Madison